Symbol: Name: ID: |
WNT4 wingless-type MMTV integration site family, member 4 GFS:2541 |
Gene name: | WNT4 |
Chromosome: | 1p36.23-p35.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | WNT-4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98957 | Rat Genome Database ID: | RGD:621348 |
HGNC ID: | HGNC:12783 | RefSeq IDs: | NM_030761 |
Entrez Gene ID: | 54361 | Ensembl Gene ID: | ENSG00000162552 |
VEGA IDs: | OTTHUMG00000002894 | UniProt ID: | P56705 |
UCSC ID: | uc001bfs.3 | OMIM ID: | 603490 |
Pubmed: | PMID8168088 | ||
CCDS IDs: | CCDSCCDS223.1 |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for WNT4 gene
Catalog | Product Name | Application | Company |
GFS:E02541 | wingless-type MMTV integration site family, member 4; ELISA kit | ELISA | n/a |
GFS:A02541 | wingless-type MMTV integration site family, member 4; Anti | ANTIBODIES | n/a |
GFS:P02541 | wingless-type MMTV integration site family, member 4; Protien | Protien | n/a |