Symbol: Name: ID: |
SMC2 structural maintenance of chromosomes 2 GFS:3446 |
Gene name: | SMC2 |
Chromosome: | 9q31.1 |
Previous Symbols: | SMC2L1 |
Previous Names: | SMC2 (structural maintenance of chromosomes 2, yeast)-like 1, "SMC2 structural maintenance of chromosomes 2-like 1 (yeast)" |
Aliases: | hCAP-E, CAP-E |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:106067 | Rat Genome Database ID: | RGD:1305227 |
HGNC ID: | HGNC:14011 | RefSeq IDs: | NM_001042550 |
Entrez Gene ID: | 10592 | Ensembl Gene ID: | ENSG00000136824 |
VEGA IDs: | OTTHUMG00000020401 | UniProt ID: | O95347 |
UCSC ID: | uc004bbw.2 | OMIM ID: | 605576 |
Pubmed: | PMID9789013 | ||
CCDS IDs: | CCDSCCDS35086.1 |
Structural maintenance of chromosomes protein 2 (SMC-2) also known as chromosome-associated protein E (CAP-E) is a protein that in humans is encoded by the SMC2 gene.
Members of the structural maintenance of chromosomes, or SMC, family (e.g., SMC1A; MIM 300040) are critical for mitotic chromosome condensation in frogs and for DNA repair in mammals.[supplied by OMIM, Nov 2010].
Function: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Products for SMC2 gene
Catalog | Product Name | Application | Company |
GFS:E03446 | structural maintenance of chromosomes 2; ELISA kit | ELISA | n/a |
GFS:A03446 | structural maintenance of chromosomes 2; Anti | ANTIBODIES | n/a |
GFS:P03446 | structural maintenance of chromosomes 2; Protien | Protien | n/a |