| Symbol: Name: ID: |
PSMC3IP PSMC3 interacting protein GFS:6826 |
| Gene name: | PSMC3IP |
| Chromosome: | 17q21.2 |
| Previous Symbols: | |
| Previous Names: | |
| Aliases: | TBPIP, GT198, HUMGT198A |
| Name Aliases: | TBP-1 interacting protein |
| Locus Type: | gene with protein product |
| Mouse Genome Database ID: | MGI:1098610 | Rat Genome Database ID: | RGD:621885 |
| HGNC ID: | HGNC:17928 | RefSeq IDs: | NM_013290 |
| Entrez Gene ID: | 29893 | Ensembl Gene ID: | ENSG00000131470 |
| VEGA IDs: | UniProt ID: | Q9P2W1 | |
| UCSC ID: | uc002iai.2 | OMIM ID: | 608665 |
| Pubmed: | PMID7490091 PMID 10806355 PMID 11739747 | ||
| CCDS IDs: | CCDSCCDS11431.1 CCDS CCDS45688.1 | ||
Function: Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
Products for PSMC3IP gene
| Catalog | Product Name | Application | Company |
| GFS:E06826 | PSMC3 interacting protein; ELISA kit | ELISA | n/a |
| GFS:A06826 | PSMC3 interacting protein; Anti | ANTIBODIES | n/a |
| GFS:P06826 | PSMC3 interacting protein; Protien | Protien | n/a |
