Symbol: Name: ID: |
SLC9A1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 GFS:985 |
Gene name: | SLC9A1 |
Chromosome: | 1p36.1-p35 |
Previous Symbols: | APNH, NHE1 |
Previous Names: | solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive) |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:102462 | Rat Genome Database ID: | RGD:3718 |
HGNC ID: | HGNC:11071 | RefSeq IDs: | NM_003047 |
Entrez Gene ID: | 6548 | Ensembl Gene ID: | ENSG00000090020 |
VEGA IDs: | OTTHUMG00000004271 | UniProt ID: | P19634 |
UCSC ID: | uc001bnm.2 | OMIM ID: | 107310 |
Pubmed: | PMID8283968 | ||
CCDS IDs: | CCDSCCDS295.1 |
The sodium-hydrogen antiporter 1 (NHE-1) also known as sodium/hydrogen exchanger 1 or SLC9A1 (SoLute Carrier family 9A1) is an isoform of sodium–hydrogen antiporter that in humans is encoded by the SLC9A1 gene. The Na+/H+ antiporter (SLC9A1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, tumor promoters, and others (Mattei et al., 1988 [PubMed 2846238]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Products for SLC9A1 gene
Catalog | Product Name | Application | Company |
GFS:E00985 | solute carrier family 9 (sodium/hydrogen exchanger), member 1; ELISA kit | ELISA | n/a |
GFS:A00985 | solute carrier family 9 (sodium/hydrogen exchanger), member 1; Anti | ANTIBODIES | n/a |
GFS:P00985 | solute carrier family 9 (sodium/hydrogen exchanger), member 1; Protien | Protien | n/a |