Symbol: Name: ID: |
SLC16A3 solute carrier family 16, member 3 (monocarboxylic acid transporter 4) GFS:834 |
Gene name: | SLC16A3 |
Chromosome: | 17q25 |
Previous Symbols: | |
Previous Names: | solute carrier family 16 (monocarboxylic acid transporters), member 3 |
Aliases: | MCT3, MCT4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1933438 | Rat Genome Database ID: | RGD:620603 |
HGNC ID: | HGNC:10924 | RefSeq IDs: | NM_001042422 |
Entrez Gene ID: | 9123 | Ensembl Gene ID: | ENSG00000141526 |
VEGA IDs: | UniProt ID: | O15427 | |
UCSC ID: | uc002kea.2 | OMIM ID: | 603877 |
Pubmed: | PMID9425115 | ||
CCDS IDs: | CCDSCCDS11804.1 |
Monocarboxylate transporter 4 is a protein that in humans is encoded by the SLC16A3 gene. Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM].
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
Products for SLC16A3 gene
Catalog | Product Name | Application | Company |
GFS:E00834 | solute carrier family 16, member 3 (monocarboxylic acid transporter 4); ELISA kit | ELISA | n/a |
GFS:A00834 | solute carrier family 16, member 3 (monocarboxylic acid transporter 4); Anti | ANTIBODIES | n/a |
GFS:P00834 | solute carrier family 16, member 3 (monocarboxylic acid transporter 4); Protien | Protien | n/a |