Symbol: Name: ID: |
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 GFS:814 |
Gene name: | SLC10A1 |
Chromosome: | 14q24 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NTCP |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:97379 | Rat Genome Database ID: | RGD:3681 |
HGNC ID: | HGNC:10905 | RefSeq IDs: | NM_003049 |
Entrez Gene ID: | 6554 | Ensembl Gene ID: | ENSG00000100652 |
VEGA IDs: | UniProt ID: | Q14973 | |
UCSC ID: | uc001xlr.2 | OMIM ID: | 182396 |
Pubmed: | PMID8132774 | ||
CCDS IDs: | CCDSCCDS9797.1 |
Sodium/bile acid cotransporter also known as the Na+-taurocholate cotransporting polypeptide (NTCP) or liver bile acid transporter (LBAT) is a protein that in humans is encoded by the SLC10A1 (solute carrier family 10 member 1) gene. Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization (SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
Products for SLC10A1 gene
Catalog | Product Name | Application | Company |
GFS:E00814 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1; ELISA kit | ELISA | n/a |
GFS:A00814 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1; Anti | ANTIBODIES | n/a |
GFS:P00814 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1; Protien | Protien | n/a |