Symbol: Name: ID: |
SLC7A6 solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 GFS:977 |
Gene name: | SLC7A6 |
Chromosome: | 16q22.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | y+LAT-2, KIAA0245, LAT3, LAT-2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2142598 | Rat Genome Database ID: | RGD:1309193 |
HGNC ID: | HGNC:11064 | RefSeq IDs: | NM_001076785 |
Entrez Gene ID: | 9057 | Ensembl Gene ID: | ENSG00000103064 |
VEGA IDs: | UniProt ID: | Q92536 | |
UCSC ID: | uc002evu.1 | OMIM ID: | 605641 |
Pubmed: | PMID9878049 | ||
CCDS IDs: | CCDSCCDS32470.1 |
Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
Products for SLC7A6 gene
Catalog | Product Name | Application | Company |
GFS:E00977 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 6; ELISA kit | ELISA | n/a |
GFS:A00977 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 6; Anti | ANTIBODIES | n/a |
GFS:P00977 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 6; Protien | Protien | n/a |