Symbol: Name: ID: |
SLC7A5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 GFS:976 |
Gene name: | SLC7A5 |
Chromosome: | 16q24.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | LAT1, E16, D16S469E, MPE16, CD98 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1298205 | Rat Genome Database ID: | RGD:620639 |
HGNC ID: | HGNC:11063 | RefSeq IDs: | NM_003486 |
Entrez Gene ID: | 8140 | Ensembl Gene ID: | ENSG00000103257 |
VEGA IDs: | OTTHUMG00000137658 | UniProt ID: | Q01650 |
UCSC ID: | uc002fkm.2 | OMIM ID: | 600182 |
Pubmed: | PMID9751058 PMID 7829099 | ||
CCDS IDs: | CCDSCCDS10964.1 |
Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts
Products for SLC7A5 gene
Catalog | Product Name | Application | Company |
GFS:E00976 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; ELISA kit | ELISA | n/a |
GFS:A00976 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; Anti | ANTIBODIES | n/a |
GFS:P00976 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5; Protien | Protien | n/a |