Symbol: Name: ID: |
SLC7A8 solute carrier family 7 (amino acid transporter, L-type), member 8 GFS:979 |
Gene name: | SLC7A8 |
Chromosome: | 14q11.2 |
Previous Symbols: | |
Previous Names: | solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 |
Aliases: | LPI-PC1, LAT2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1355323 | Rat Genome Database ID: | RGD:619904 |
HGNC ID: | HGNC:11066 | RefSeq IDs: | NM_012244 |
Entrez Gene ID: | 23428 | Ensembl Gene ID: | ENSG00000092068 |
VEGA IDs: | OTTHUMG00000028720 | UniProt ID: | Q9UHI5 |
UCSC ID: | uc001wiz.2 | OMIM ID: | 604235 |
Pubmed: | PMID10080183 PMID 10391915 | ||
CCDS IDs: | CCDSCCDS9590.1 CCDS CCDS41924.1 |
Large neutral amino acids transporter small subunit 2 is a protein that in humans is encoded by the SLC7A8 gene. cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney.
Products for SLC7A8 gene
Catalog | Product Name | Application | Company |
GFS:E00979 | solute carrier family 7 (amino acid transporter, L-type), member 8; ELISA kit | ELISA | n/a |
GFS:A00979 | solute carrier family 7 (amino acid transporter, L-type), member 8; Anti | ANTIBODIES | n/a |
GFS:P00979 | solute carrier family 7 (amino acid transporter, L-type), member 8; Protien | Protien | n/a |