Symbol: Name: ID: |
SLC6A5 solute carrier family 6 (neurotransmitter transporter, glycine), member 5 GFS:963 |
Gene name: | SLC6A5 |
Chromosome: | 11p15.1 |
Previous Symbols: | NET1 |
Previous Names: | |
Aliases: | GLYT2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:105090 | Rat Genome Database ID: | RGD:621824 |
HGNC ID: | HGNC:11051 | RefSeq IDs: | NM_004211 |
Entrez Gene ID: | 9152 | Ensembl Gene ID: | ENSG00000165970 |
VEGA IDs: | UniProt ID: | Q9Y345 | |
UCSC ID: | uc001mqd.2 | OMIM ID: | 604159 |
Pubmed: | PMID9845349 | ||
CCDS IDs: | CCDSCCDS7854.1 |
Glycine transporter 2 (GlyT2) also known as the sodium- and chloride-dependent glycine transporter 2 or solute carrier family 6 member 5 is a protein that in humans is encoded by the SLC6A5 gene. This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses.
Products for SLC6A5 gene
Catalog | Product Name | Application | Company |
GFS:E00963 | solute carrier family 6 (neurotransmitter transporter, glycine), member 5; ELISA kit | ELISA | n/a |
GFS:A00963 | solute carrier family 6 (neurotransmitter transporter, glycine), member 5; Anti | ANTIBODIES | n/a |
GFS:P00963 | solute carrier family 6 (neurotransmitter transporter, glycine), member 5; Protien | Protien | n/a |