Symbol: Name: ID: |
SLC5A7 solute carrier family 5 (choline transporter), member 7 GFS:3459 |
Gene name: | SLC5A7 |
Chromosome: | 2q12 |
Previous Symbols: | |
Previous Names: | |
Aliases: | hCHT, CHT1 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1927126 | Rat Genome Database ID: | RGD:69270 |
HGNC ID: | HGNC:14025 | RefSeq IDs: | NM_021815 |
Entrez Gene ID: | 60482 | Ensembl Gene ID: | ENSG00000115665 |
VEGA IDs: | OTTHUMG00000130959 | UniProt ID: | Q9GZV3 |
UCSC ID: | uc002tdv.2 | OMIM ID: | 608761 |
Pubmed: | PMID11027560 | ||
CCDS IDs: | CCDSCCDS2074.1 |
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion-dependent.
Products for SLC5A7 gene
Catalog | Product Name | Application | Company |
GFS:E03459 | solute carrier family 5 (choline transporter), member 7; ELISA kit | ELISA | n/a |
GFS:A03459 | solute carrier family 5 (choline transporter), member 7; Anti | ANTIBODIES | n/a |
GFS:P03459 | solute carrier family 5 (choline transporter), member 7; Protien | Protien | n/a |