Symbol: Name: ID: |
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 GFS:944 |
Gene name: | SLC4A8 |
Chromosome: | 12q13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NBC3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1928745 | Rat Genome Database ID: | RGD:735164 |
HGNC ID: | HGNC:11034 | RefSeq IDs: | NM_001039960 |
Entrez Gene ID: | 9498 | Ensembl Gene ID: | ENSG00000050438 |
VEGA IDs: | UniProt ID: | Q2Y0W8 | |
UCSC ID: | uc001rys.1 | OMIM ID: | 605024 |
Pubmed: | PMID11133997 | ||
CCDS IDs: | CCDSCCDS8814.1 CCDS CCDS44890.1 |
Electroneutral sodium bicarbonate exchanger 1 is a protein that in humans is encoded by the SLC4A8 gene. Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.
Products for SLC4A8 gene
Catalog | Product Name | Application | Company |
GFS:E00944 | solute carrier family 4, sodium bicarbonate cotransporter, member 8; ELISA kit | ELISA | n/a |
GFS:A00944 | solute carrier family 4, sodium bicarbonate cotransporter, member 8; Anti | ANTIBODIES | n/a |
GFS:P00944 | solute carrier family 4, sodium bicarbonate cotransporter, member 8; Protien | Protien | n/a |