Symbol: Name: ID: |
SLC4A5 solute carrier family 4, sodium bicarbonate cotransporter, member 5 GFS:7054 |
Gene name: | SLC4A5 |
Chromosome: | 2p13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NBC4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2443220 | Rat Genome Database ID: | RGD:1303009 |
HGNC ID: | HGNC:18168 | RefSeq IDs: | NM_021196 |
Entrez Gene ID: | 57835 | Ensembl Gene ID: | ENSG00000188687 |
VEGA IDs: | OTTHUMG00000090263 | UniProt ID: | Q9BY07 |
UCSC ID: | uc002sko.1 | OMIM ID: | 606757 |
Pubmed: | PMID10978526 PMID 11087115 | ||
CCDS IDs: | CCDSCCDS1936.1 CCDS CCDS1937.1 |
Electrogenic sodium bicarbonate cotransporter 4 is a protein that in humans is encoded by the SLC4A5 gene.
This gene encodes a member of the sodium bicarbonate cotransporter (NBC) family, part of the bicarbonate transporter superfamily. Sodium bicarbonate cotransporters are involved in intracellular pH regulation and electroneural or electrogenic sodium bicarbonate transport. This protein is thought to be an integral membrane protein. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
Function: Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry of 2:1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na(+):HCO3(-) cotransport in hepatocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH.
Products for SLC4A5 gene
Catalog | Product Name | Application | Company |
GFS:E07054 | solute carrier family 4, sodium bicarbonate cotransporter, member 5; ELISA kit | ELISA | n/a |
GFS:A07054 | solute carrier family 4, sodium bicarbonate cotransporter, member 5; Anti | ANTIBODIES | n/a |
GFS:P07054 | solute carrier family 4, sodium bicarbonate cotransporter, member 5; Protien | Protien | n/a |