Symbol: Name: ID: |
SLC38A4 solute carrier family 38, member 4 GFS:3963 |
Gene name: | SLC38A4 |
Chromosome: | 12q13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PAAT, NAT3, ATA3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1916604 | Rat Genome Database ID: | RGD:621836 |
HGNC ID: | HGNC:14679 | RefSeq IDs: | NM_001143824 |
Entrez Gene ID: | 55089 | Ensembl Gene ID: | ENSG00000139209 |
VEGA IDs: | UniProt ID: | Q969I6 | |
UCSC ID: | uc001rpj.2 | OMIM ID: | 608065 |
Pubmed: | PMID11414754 | ||
CCDS IDs: | CCDSCCDS8750.1 |
SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001 [PubMed 11342143]).[supplied by OMIM, Mar 2008].
Function: Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by His, Cys, Asn, Ser, Gly, Val, Thr, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with low transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5.
Products for SLC38A4 gene
Catalog | Product Name | Application | Company |
GFS:E03963 | solute carrier family 38, member 4; ELISA kit | ELISA | n/a |
GFS:A03963 | solute carrier family 38, member 4; Anti | ANTIBODIES | n/a |
GFS:P03963 | solute carrier family 38, member 4; Protien | Protien | n/a |