Symbol: Name: ID: |
SLC35B2 solute carrier family 35, member B2 GFS:5958 |
Gene name: | SLC35B2 |
Chromosome: | 6p12.1-p11.21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | UGTrel4 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1921086 | Rat Genome Database ID: | RGD:1565318 |
HGNC ID: | HGNC:16872 | RefSeq IDs: | NM_178148 |
Entrez Gene ID: | 347734 | Ensembl Gene ID: | ENSG00000157593 |
VEGA IDs: | OTTHUMG00000014760 | UniProt ID: | Q8TB61 |
UCSC ID: | uc003oxd.2 | OMIM ID: | 610788 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS34462.1 |
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 is a protein that in humans is encoded by the SLC35B2 gene.
Sulfotransferases (e.g., SULT4A1; MIM 608359) use an activated form of sulfate, 3-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS), as a common sulfate donor for sulfation of glycoproteins, proteoglycans, and glycolipids in the endoplasmic reticulum and Golgi apparatus. SLC35B2 is located in the microsomal membrane and transports PAPS from the cytosol, where it is synthesized, into the Golgi lumen (Kamiyama et al., 2003 [PubMed 12716889]).[supplied by OMIM, Mar 2008].
Function: Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. May indirectly participate in activation of the NF-kappa-B and MAPK pathways.
Products for SLC35B2 gene
Catalog | Product Name | Application | Company |
GFS:E05958 | solute carrier family 35, member B2; ELISA kit | ELISA | n/a |
GFS:A05958 | solute carrier family 35, member B2; Anti | ANTIBODIES | n/a |
GFS:P05958 | solute carrier family 35, member B2; Protien | Protien | n/a |