Symbol: Name: ID: |
SLC31A1 solute carrier family 31 (copper transporters), member 1 GFS:926 |
Gene name: | SLC31A1 |
Chromosome: | 9q31-q32 |
Previous Symbols: | COPT1 |
Previous Names: | |
Aliases: | hCTR1, CTR1 |
Name Aliases: | copper transport 1 homolog (S. cerevisiae) |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1333843 | Rat Genome Database ID: | RGD:620059 |
HGNC ID: | HGNC:11016 | RefSeq IDs: | NM_001859 |
Entrez Gene ID: | 1317 | Ensembl Gene ID: | ENSG00000136868 |
VEGA IDs: | OTTHUMG00000020519 | UniProt ID: | O15431 |
UCSC ID: | uc004bgu.2 | OMIM ID: | 603085 |
Pubmed: | PMID9207117 | ||
CCDS IDs: | CCDSCCDS6789.1 |
High affinity copper uptake protein 1 is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Products for SLC31A1 gene
Catalog | Product Name | Application | Company |
GFS:E00926 | solute carrier family 31 (copper transporters), member 1; ELISA kit | ELISA | n/a |
GFS:A00926 | solute carrier family 31 (copper transporters), member 1; Anti | ANTIBODIES | n/a |
GFS:P00926 | solute carrier family 31 (copper transporters), member 1; Protien | Protien | n/a |