Symbol: Name: ID: |
SLC28A3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 GFS:5591 |
Gene name: | SLC28A3 |
Chromosome: | 9q21.33 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CNT3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2137361 | Rat Genome Database ID: | RGD:621224 |
HGNC ID: | HGNC:16484 | RefSeq IDs: | NM_001199633 |
Entrez Gene ID: | 64078 | Ensembl Gene ID: | ENSG00000197506 |
VEGA IDs: | OTTHUMG00000020117 | UniProt ID: | Q9HAS3 |
UCSC ID: | uc004anu.1 | OMIM ID: | 608269 |
Pubmed: | PMID11032837 | ||
CCDS IDs: | CCDSCCDS6670.1 |
Nucleoside transporters, such as SLC28A3, regulate multiple cellular processes, including neurotransmission, vascular tone, adenosine concentration in the vicinity of cell surface receptors, and transport and metabolism of nucleoside drugs. SLC28A3 shows broad specificity for pyrimidine and purine nucleosides (Ritzel et al., 2001 [PubMed 11032837]).[supplied by OMIM, Mar 2008].
Function: Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine.
Products for SLC28A3 gene
Catalog | Product Name | Application | Company |
GFS:E05591 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; ELISA kit | ELISA | n/a |
GFS:A05591 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Anti | ANTIBODIES | n/a |
GFS:P05591 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Protien | Protien | n/a |