Symbol: Name: ID: |
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 GFS:903 |
Gene name: | SLC27A1 |
Chromosome: | 19p13.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | FATP1, FATP, MGC71751, FLJ00336, ACSVL5 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1347098 | Rat Genome Database ID: | RGD:620927 |
HGNC ID: | HGNC:10995 | RefSeq IDs: | NM_198580 |
Entrez Gene ID: | 376497 | Ensembl Gene ID: | ENSG00000130304 |
VEGA IDs: | UniProt ID: | Q6PCB7 | |
UCSC ID: | uc002ngu.1 | OMIM ID: | 600691 |
Pubmed: | PMID10873384 | ||
CCDS IDs: | CCDSCCDS32953.1 |
Long-chain fatty acid transport protein 1 is a protein that in humans is encoded by the SLC27A1 gene. Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity).
Products for SLC27A1 gene
Catalog | Product Name | Application | Company |
GFS:E00903 | solute carrier family 27 (fatty acid transporter), member 1; ELISA kit | ELISA | n/a |
GFS:A00903 | solute carrier family 27 (fatty acid transporter), member 1; Anti | ANTIBODIES | n/a |
GFS:P00903 | solute carrier family 27 (fatty acid transporter), member 1; Protien | Protien | n/a |