Symbol: Name: ID: |
SLC26A8 solute carrier family 26, member 8 GFS:3798 |
Gene name: | SLC26A8 |
Chromosome: | 6p21 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2385046 | Rat Genome Database ID: | RGD:1308898 |
HGNC ID: | HGNC:14468 | RefSeq IDs: | NM_001193476 |
Entrez Gene ID: | 116369 | Ensembl Gene ID: | ENSG00000112053 |
VEGA IDs: | OTTHUMG00000014586 | UniProt ID: | Q96RN1 |
UCSC ID: | uc003oln.2 | OMIM ID: | 608480 |
Pubmed: | PMID11834742 PMID 11829495 | ||
CCDS IDs: | CCDSCCDS4813.1 CCDS CCDS4814.1 |
Testis anion transporter 1 is a protein that in humans is encoded by the SLC26A8 gene.
This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010].
Function: Acts as a DIDS-sensitive anion exchanger mediating chloride, sulfate and oxalate transport. May fulfill critical anion exchange functions in male germ line during meiosis and hence may play a role in spermatogenesis. May be involved in a new regulatory pathway linking sulfate transport to RhoGTPase signaling in male germ cells. A critical component of the sperm annulus that is essential for correct sperm tail differentiation and motility and hence male fertility.
Products for SLC26A8 gene
Catalog | Product Name | Application | Company |
GFS:E03798 | solute carrier family 26, member 8; ELISA kit | ELISA | n/a |
GFS:A03798 | solute carrier family 26, member 8; Anti | ANTIBODIES | n/a |
GFS:P03798 | solute carrier family 26, member 8; Protien | Protien | n/a |