Symbol: Name: ID: |
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 GFS:892 |
Gene name: | SLC25A15 |
Chromosome: | 13q14 |
Previous Symbols: | ORNT1, HHH |
Previous Names: | |
Aliases: | ORC1, D13S327 |
Name Aliases: | ornithine transporter 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1342274 | Rat Genome Database ID: | RGD:1311488 |
HGNC ID: | HGNC:10985 | RefSeq IDs: | NM_014252 |
Entrez Gene ID: | 10166 | Ensembl Gene ID: | ENSG00000102743 |
VEGA IDs: | OTTHUMG00000016776 | UniProt ID: | Q9Y619 |
UCSC ID: | uc001uxn.2 | OMIM ID: | 603861 |
Pubmed: | PMID10369256 | ||
CCDS IDs: | CCDSCCDS9373.1 |
SLC25A15 is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.
Products for SLC25A15 gene
Catalog | Product Name | Application | Company |
GFS:E00892 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15; ELISA kit | ELISA | n/a |
GFS:A00892 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15; Anti | ANTIBODIES | n/a |
GFS:P00892 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15; Protien | Protien | n/a |