Symbol: Name: ID: |
SLC25A13 solute carrier family 25, member 13 (citrin) GFS:890 |
Gene name: | SLC25A13 |
Chromosome: | 7q21.3 |
Previous Symbols: | CTLN2 |
Previous Names: | |
Aliases: | CITRIN, ARALAR2 |
Name Aliases: | mitochondrial aspartate glutamate carrier 2 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1354721 | Rat Genome Database ID: | RGD:1565889 |
HGNC ID: | HGNC:10983 | RefSeq IDs: | NM_001160210 |
Entrez Gene ID: | 10165 | Ensembl Gene ID: | ENSG00000004864 |
VEGA IDs: | OTTHUMG00000023074 | UniProt ID: | Q9UJS0 |
UCSC ID: | uc003uog.3 | OMIM ID: | 603859 |
Pubmed: | PMID10369257 | ||
CCDS IDs: | CCDSCCDS5645.1 |
SLC25A13 is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Function: Calcium-dependent mitochondrial aspartate and glutamate carrier. May have a function in the urea cycle.
Products for SLC25A13 gene
Catalog | Product Name | Application | Company |
GFS:E00890 | solute carrier family 25, member 13 (citrin); ELISA kit | ELISA | n/a |
GFS:A00890 | solute carrier family 25, member 13 (citrin); Anti | ANTIBODIES | n/a |
GFS:P00890 | solute carrier family 25, member 13 (citrin); Protien | Protien | n/a |