Symbol: Name: ID: |
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 GFS:3588 |
Gene name: | SLC25A20 |
Chromosome: | 3p21.31 |
Previous Symbols: | CACT |
Previous Names: | |
Aliases: | CAC |
Name Aliases: | carnitine-acylcarnitine carrier, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1928738 | Rat Genome Database ID: | RGD:621443 |
HGNC ID: | HGNC:1421 | RefSeq IDs: | NM_000387 |
Entrez Gene ID: | 788 | Ensembl Gene ID: | ENSG00000178537 |
VEGA IDs: | OTTHUMG00000133538 | UniProt ID: | O43772 |
UCSC ID: | uc003cva.3 | OMIM ID: | 613698 |
Pubmed: | PMID9399886 PMID 9533014 | ||
CCDS IDs: | CCDSCCDS2779.1 |
This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Mediates the transport of acylcarnitines of different length across the mitochondrial inner membrane from the cytosol to the mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway.
Products for SLC25A20 gene
Catalog | Product Name | Application | Company |
GFS:E03588 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20; ELISA kit | ELISA | n/a |
GFS:A03588 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20; Anti | ANTIBODIES | n/a |
GFS:P03588 | solute carrier family 25 (carnitine/acylcarnitine translocase), member 20; Protien | Protien | n/a |