Symbol: Name: ID: |
SLC22A4 solute carrier family 22 (organic cation/ergothioneine transporter), member 4 GFS:874 |
Gene name: | SLC22A4 |
Chromosome: | 5q23.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | OCTN1, MGC34546 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1353479 | Rat Genome Database ID: | |
HGNC ID: | HGNC:10968 | RefSeq IDs: | NM_003059 |
Entrez Gene ID: | 6583 | Ensembl Gene ID: | ENSG00000197208 |
VEGA IDs: | OTTHUMG00000059648 | UniProt ID: | Q9H015 |
UCSC ID: | uc003kwq.2 | OMIM ID: | 604190 |
Pubmed: | PMID9426230 PMID 15795384 | ||
CCDS IDs: | CCDSCCDS4153.1 |
Solute carrier family 22, member 4, also known as SLC22A4, is a human gene; the encoded protein is an ergothioneine transporter. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78. A key substrate of this transporter seems to be ergothioneine (ET).
Products for SLC22A4 gene
Catalog | Product Name | Application | Company |
GFS:E00874 | solute carrier family 22 (organic cation/ergothioneine transporter), member 4; ELISA kit | ELISA | n/a |
GFS:A00874 | solute carrier family 22 (organic cation/ergothioneine transporter), member 4; Anti | ANTIBODIES | n/a |
GFS:P00874 | solute carrier family 22 (organic cation/ergothioneine transporter), member 4; Protien | Protien | n/a |