Symbol: Name: ID: |
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 GFS:879 |
Gene name: | SLC22A8 |
Chromosome: | 11q12.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | OAT3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1336187 | Rat Genome Database ID: | RGD:632286 |
HGNC ID: | HGNC:10972 | RefSeq IDs: | NM_001184732 |
Entrez Gene ID: | 9376 | Ensembl Gene ID: | ENSG00000149452 |
VEGA IDs: | UniProt ID: | Q8TCC7 | |
UCSC ID: | uc001nwo.2 | OMIM ID: | 607581 |
Pubmed: | PMID10049739 | ||
CCDS IDs: | CCDSCCDS8042.1 |
Solute carrier family 22 member 8 is a protein that in humans is encoded by the SLC22A8 gene. This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq].
Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
Products for SLC22A8 gene
Catalog | Product Name | Application | Company |
GFS:E00879 | solute carrier family 22 (organic anion transporter), member 8; ELISA kit | ELISA | n/a |
GFS:A00879 | solute carrier family 22 (organic anion transporter), member 8; Anti | ANTIBODIES | n/a |
GFS:P00879 | solute carrier family 22 (organic anion transporter), member 8; Protien | Protien | n/a |