Symbol: Name: ID: |
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 GFS:3765 |
Gene name: | SLC13A3 |
Chromosome: | 20q12-q13.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | NADC3, SDCT2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2149635 | Rat Genome Database ID: | RGD:628786 |
HGNC ID: | HGNC:14430 | RefSeq IDs: | NM_001011554 |
Entrez Gene ID: | 64849 | Ensembl Gene ID: | ENSG00000158296 |
VEGA IDs: | OTTHUMG00000033042 | UniProt ID: | Q8WWT9 |
UCSC ID: | uc002xsf.1 | OMIM ID: | 606411 |
Pubmed: | PMID10794676 PMID 10992006 | ||
CCDS IDs: | CCDSCCDS13400.1 CCDS CCDS42886.1 |
Solute carrier family 13 member 3 also called sodium-dependent dicarboxylate transporter (NaDC3) is a protein that in humans is encoded by the SLC13A3 gene.
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet. [provided by RefSeq, Jul 2008].
Function: High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate.
Products for SLC13A3 gene
Catalog | Product Name | Application | Company |
GFS:E03765 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3; ELISA kit | ELISA | n/a |
GFS:A03765 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3; Anti | ANTIBODIES | n/a |
GFS:P03765 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3; Protien | Protien | n/a |