Symbol: Name: ID: |
SFRP5 secreted frizzled-related protein 5 GFS:697 |
Gene name: | SFRP5 |
Chromosome: | 10q24 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SARP3 |
Name Aliases: | secreted apoptosis related protein 3 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1860298 | Rat Genome Database ID: | RGD:1310369 |
HGNC ID: | HGNC:10779 | RefSeq IDs: | NM_003015 |
Entrez Gene ID: | 6425 | Ensembl Gene ID: | ENSG00000120057 |
VEGA IDs: | OTTHUMG00000018866 | UniProt ID: | Q5T4F7 |
UCSC ID: | uc001kor.3 | OMIM ID: | 604158 |
Pubmed: | PMID9391078 | ||
CCDS IDs: | CCDSCCDS7472.1 |
Secreted frizzled-related protein 5 is a protein that in humans is encoded by the SFRP5 gene. Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina
Products for SFRP5 gene
Catalog | Product Name | Application | Company |
GFS:E00697 | secreted frizzled-related protein 5; ELISA kit | ELISA | n/a |
GFS:A00697 | secreted frizzled-related protein 5; Anti | ANTIBODIES | n/a |
GFS:P00697 | secreted frizzled-related protein 5; Protien | Protien | n/a |