Symbol: Name: ID: |
SFRP4 secreted frizzled-related protein 4 GFS:696 |
Gene name: | SFRP4 |
Chromosome: | 7p14.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | frpHE, FRP-4, FRPHE |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:892010 | Rat Genome Database ID: | RGD:621075 |
HGNC ID: | HGNC:10778 | RefSeq IDs: | NM_003014 |
Entrez Gene ID: | 6424 | Ensembl Gene ID: | ENSG00000106483 |
VEGA IDs: | OTTHUMG00000023026 | UniProt ID: | Q6FHJ7 |
UCSC ID: | uc003tfo.3 | OMIM ID: | 606570 |
Pubmed: | PMID10211996 | ||
CCDS IDs: | CCDSCCDS5453.1 |
Secreted frizzled-related protein 4 is a protein that in humans is encoded by the SFRP4 gene. Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake
Products for SFRP4 gene
Catalog | Product Name | Application | Company |
GFS:E00696 | secreted frizzled-related protein 4; ELISA kit | ELISA | n/a |
GFS:A00696 | secreted frizzled-related protein 4; Anti | ANTIBODIES | n/a |
GFS:P00696 | secreted frizzled-related protein 4; Protien | Protien | n/a |