Symbol: Name: ID: |
SFRP2 secreted frizzled-related protein 2 GFS:695 |
Gene name: | SFRP2 |
Chromosome: | 4q31.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SARP1, SDF-5, FRP-2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:108078 | Rat Genome Database ID: | RGD:735163 |
HGNC ID: | HGNC:10777 | RefSeq IDs: | NM_003013 |
Entrez Gene ID: | 6423 | Ensembl Gene ID: | ENSG00000145423 |
VEGA IDs: | UniProt ID: | Q96HF1 | |
UCSC ID: | uc003inv.1 | OMIM ID: | 604157 |
Pubmed: | PMID9391078 | ||
CCDS IDs: | CCDSCCDS34082.1 |
Secreted frizzled-related protein 2 is a protein that in humans is encoded by the SFRP2 gene. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Products for SFRP2 gene
Catalog | Product Name | Application | Company |
GFS:E00695 | secreted frizzled-related protein 2; ELISA kit | ELISA | n/a |
GFS:A00695 | secreted frizzled-related protein 2; Anti | ANTIBODIES | n/a |
GFS:P00695 | secreted frizzled-related protein 2; Protien | Protien | n/a |