Symbol: Name: ID: |
PADI3 peptidyl arginine deiminase, type III GFS:7208 |
Gene name: | PADI3 |
Chromosome: | 1p36.13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | PDI3 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1338891 | Rat Genome Database ID: | RGD:3289 |
HGNC ID: | HGNC:18337 | RefSeq IDs: | NM_016233 |
Entrez Gene ID: | 51702 | Ensembl Gene ID: | ENSG00000142619 |
VEGA IDs: | OTTHUMG00000002373 | UniProt ID: | Q9ULW8 |
UCSC ID: | uc001bai.2 | OMIM ID: | 606755 |
Pubmed: | PMID11069618 | ||
CCDS IDs: | CCDSCCDS179.1 |
Peptidyl arginine deiminase, type III, also known as PADI3, is a protein which in humans is encoded by the PADI3 gene.
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Catalyzes the deimination of arginine residues of proteins.
Products for PADI3 gene
Catalog | Product Name | Application | Company |
GFS:E07208 | peptidyl arginine deiminase, type III; ELISA kit | ELISA | n/a |
GFS:A07208 | peptidyl arginine deiminase, type III; Anti | ANTIBODIES | n/a |
GFS:P07208 | peptidyl arginine deiminase, type III; Protien | Protien | n/a |