Symbol: Name: ID: |
CLDN23 claudin 23 GFS:6568 |
Gene name: | CLDN23 |
Chromosome: | 8p23.1 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CLDNL |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919158 | Rat Genome Database ID: | RGD:1309001 |
HGNC ID: | HGNC:17591 | RefSeq IDs: | NM_194284 |
Entrez Gene ID: | 137075 | Ensembl Gene ID: | ENSG00000253958 |
VEGA IDs: | UniProt ID: | Q96B33 | |
UCSC ID: | uc003wsi.2 | OMIM ID: | 609203 |
Pubmed: | PMID12736707 | ||
CCDS IDs: |
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. [provided by RefSeq, Aug 2010].
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity (By similarity).
Products for CLDN23 gene
Catalog | Product Name | Application | Company |
GFS:E06568 | claudin 23; ELISA kit | ELISA | n/a |
GFS:A06568 | claudin 23; Anti | ANTIBODIES | n/a |
GFS:P06568 | claudin 23; Protien | Protien | n/a |