Symbol: Name: ID: |
BMP7 bone morphogenetic protein 7 GFS:659 |
Gene name: | BMP7 |
Chromosome: | 20q13 |
Previous Symbols: | |
Previous Names: | |
Aliases: | OP-1 |
Name Aliases: | osteogenic protein 1 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:103302 | Rat Genome Database ID: | RGD:620743 |
HGNC ID: | HGNC:1074 | RefSeq IDs: | NM_001719 |
Entrez Gene ID: | 655 | Ensembl Gene ID: | ENSG00000101144 |
VEGA IDs: | OTTHUMG00000032812 | UniProt ID: | P18075 |
UCSC ID: | uc010gip.1 | OMIM ID: | 112267 |
Pubmed: | PMID1427904 | ||
CCDS IDs: | CCDSCCDS13455.1 |
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis
Products for BMP7 gene
Catalog | Product Name | Application | Company |
GFS:E00659 | bone morphogenetic protein 7; ELISA kit | ELISA | n/a |
GFS:A00659 | bone morphogenetic protein 7; Anti | ANTIBODIES | n/a |
GFS:P00659 | bone morphogenetic protein 7; Protien | Protien | n/a |