Symbol: Name: ID: |
ASB7 ankyrin repeat and SOCS box containing 7 GFS:6270 |
Gene name: | ASB7 |
Chromosome: | 15q26.3 |
Previous Symbols: | |
Previous Names: | ankyrin repeat and SOCS box-containing 7 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2152835 | Rat Genome Database ID: | RGD:1305154 |
HGNC ID: | HGNC:17182 | RefSeq IDs: | NM_024708 |
Entrez Gene ID: | 140460 | Ensembl Gene ID: | ENSG00000183475 |
VEGA IDs: | OTTHUMG00000149868 | UniProt ID: | Q9H672 |
UCSC ID: | uc002bwk.2 | OMIM ID: | |
Pubmed: | |||
CCDS IDs: | CCDSCCDS10387.1 CCDS CCDS10388.1 |
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Products for ASB7 gene
Catalog | Product Name | Application | Company |
GFS:E06270 | ankyrin repeat and SOCS box containing 7; ELISA kit | ELISA | n/a |
GFS:A06270 | ankyrin repeat and SOCS box containing 7; Anti | ANTIBODIES | n/a |
GFS:P06270 | ankyrin repeat and SOCS box containing 7; Protien | Protien | n/a |