Symbol: Name: ID: |
ASB5 ankyrin repeat and SOCS box containing 5 GFS:6268 |
Gene name: | ASB5 |
Chromosome: | 4q34.1 |
Previous Symbols: | |
Previous Names: | ankyrin repeat and SOCS box-containing 5 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1923544 | Rat Genome Database ID: | RGD:1565973 |
HGNC ID: | HGNC:17180 | RefSeq IDs: | NM_080874 |
Entrez Gene ID: | 140458 | Ensembl Gene ID: | ENSG00000164122 |
VEGA IDs: | UniProt ID: | Q8WWX0 | |
UCSC ID: | uc003iuq.1 | OMIM ID: | |
Pubmed: | |||
CCDS IDs: | CCDSCCDS3827.1 |
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008].
Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity).
Products for ASB5 gene
Catalog | Product Name | Application | Company |
GFS:E06268 | ankyrin repeat and SOCS box containing 5; ELISA kit | ELISA | n/a |
GFS:A06268 | ankyrin repeat and SOCS box containing 5; Anti | ANTIBODIES | n/a |
GFS:P06268 | ankyrin repeat and SOCS box containing 5; Protien | Protien | n/a |