Symbol: Name: ID: |
ASB6 ankyrin repeat and SOCS box containing 6 GFS:6269 |
Gene name: | ASB6 |
Chromosome: | 9q34.13 |
Previous Symbols: | |
Previous Names: | ankyrin repeat and SOCS box-containing 6 |
Aliases: | |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1919573 | Rat Genome Database ID: | RGD:1308445 |
HGNC ID: | HGNC:17181 | RefSeq IDs: | NM_001202403 |
Entrez Gene ID: | 140459 | Ensembl Gene ID: | ENSG00000148331 |
VEGA IDs: | OTTHUMG00000020787 | UniProt ID: | Q9NWX5 |
UCSC ID: | uc004byf.1 | OMIM ID: | |
Pubmed: | |||
CCDS IDs: | CCDSCCDS6924.1 CCDS CCDS6925.1 |
Ankyrin repeat and SOCS box protein 6 is a protein that in humans is encoded by the ASB6 gene.
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011].
Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Products for ASB6 gene
Catalog | Product Name | Application | Company |
GFS:E06269 | ankyrin repeat and SOCS box containing 6; ELISA kit | ELISA | n/a |
GFS:A06269 | ankyrin repeat and SOCS box containing 6; Anti | ANTIBODIES | n/a |
GFS:P06269 | ankyrin repeat and SOCS box containing 6; Protien | Protien | n/a |