Symbol: Name: ID: |
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 GFS:2580 |
Gene name: | XRCC2 |
Chromosome: | 7q36 |
Previous Symbols: | |
Previous Names: | |
Aliases: | |
Name Aliases: | RAD51-like |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1927345 | Rat Genome Database ID: | RGD:1564823 |
HGNC ID: | HGNC:12829 | RefSeq IDs: | NM_005431 |
Entrez Gene ID: | 7516 | Ensembl Gene ID: | ENSG00000196584 |
VEGA IDs: | OTTHUMG00000151470 | UniProt ID: | O43543 |
UCSC ID: | uc003wld.2 | OMIM ID: | 600375 |
Pubmed: | PMID7607692 PMID 10422536 | ||
CCDS IDs: | CCDSCCDS5933.1 |
DNA repair protein XRCC2 is a protein that in humans is encoded by the XRCC2 gene.
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Products for XRCC2 gene
Catalog | Product Name | Application | Company |
GFS:E02580 | X-ray repair complementing defective repair in Chinese hamster cells 2; ELISA kit | ELISA | n/a |
GFS:A02580 | X-ray repair complementing defective repair in Chinese hamster cells 2; Anti | ANTIBODIES | n/a |
GFS:P02580 | X-ray repair complementing defective repair in Chinese hamster cells 2; Protien | Protien | n/a |