Symbol: Name: ID: |
TRAF5 TNF receptor-associated factor 5 GFS:1832 |
Gene name: | TRAF5 |
Chromosome: | 1q32 |
Previous Symbols: | |
Previous Names: | |
Aliases: | RNF84 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:107548 | Rat Genome Database ID: | |
HGNC ID: | HGNC:12035 | RefSeq IDs: | NM_001033910 |
Entrez Gene ID: | 7188 | Ensembl Gene ID: | ENSG00000082512 |
VEGA IDs: | OTTHUMG00000036997 | UniProt ID: | O00463 |
UCSC ID: | uc001hii.2 | OMIM ID: | 602356 |
Pubmed: | PMID9126477 | ||
CCDS IDs: | CCDSCCDS1497.1 |
TNF receptor-associated factor 5 is a protein that in humans is encoded by the TRAF5 gene. The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized. [provided by RefSeq].
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis.
Products for TRAF5 gene
Catalog | Product Name | Application | Company |
GFS:E01832 | TNF receptor-associated factor 5; ELISA kit | ELISA | n/a |
GFS:A01832 | TNF receptor-associated factor 5; Anti | ANTIBODIES | n/a |
GFS:P01832 | TNF receptor-associated factor 5; Protien | Protien | n/a |