Symbol: Name: ID: |
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 GFS:6970 |
Gene name: | ST3GAL6 |
Chromosome: | 3q12.2 |
Previous Symbols: | SIAT10 |
Previous Names: | sialyltransferase 10 (alpha-2,3-sialyltransferase VI) |
Aliases: | ST3GALVI |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1888707 | Rat Genome Database ID: | RGD:1303279 |
HGNC ID: | HGNC:18080 | RefSeq IDs: | NM_006100 |
Entrez Gene ID: | 10402 | Ensembl Gene ID: | ENSG00000064225 |
VEGA IDs: | OTTHUMG00000159047 | UniProt ID: | Q9Y274 |
UCSC ID: | uc003dtc.2 | OMIM ID: | 607156 |
Pubmed: | PMID10206952 | ||
CCDS IDs: | CCDSCCDS2933.1 |
Sialyltransferases, such as ST3GAL6, catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types.[supplied by OMIM, Mar 2008].
Function: Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.
Products for ST3GAL6 gene
Catalog | Product Name | Application | Company |
GFS:E06970 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6; ELISA kit | ELISA | n/a |
GFS:A06970 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Anti | ANTIBODIES | n/a |
GFS:P06970 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Protien | Protien | n/a |