Symbol: Name: ID: |
DST dystonin GFS:808 |
Gene name: | DST |
Chromosome: | 6p12.1 |
Previous Symbols: | BPAG1 |
Previous Names: | bullous pemphigoid antigen 1, 230/240kDa |
Aliases: | BP240, KIAA0728, FLJ21489, FLJ13425, FLJ32235, FLJ30627, CATX-15, BPA, MACF2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:104627 | Rat Genome Database ID: | RGD:1306566 |
HGNC ID: | HGNC:1090 | RefSeq IDs: | NM_001723 |
Entrez Gene ID: | 667 | Ensembl Gene ID: | ENSG00000151914 |
VEGA IDs: | OTTHUMG00000014913 | UniProt ID: | Q03001 |
UCSC ID: | uc003pdf.2 | OMIM ID: | 113810 |
Pubmed: | PMID2461961 PMID 2276744 | ||
CCDS IDs: | CCDSCCDS4959.1 CCDS CCDS47443.1 |
Bullous pemphigoid antigen 1, isoforms 1/2/3/4/5/8 is a protein that in humans is encoded by the DST gene. This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration. (provided by RefSeq)
Cytoskeletal linker protein. Anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. The proteins may self-aggregate to form filaments or a two-dimensional mesh
Products for DST gene
Catalog | Product Name | Application | Company |
GFS:E00808 | dystonin; ELISA kit | ELISA | n/a |
GFS:A00808 | dystonin; Anti | ANTIBODIES | n/a |
GFS:P00808 | dystonin; Protien | Protien | n/a |