Symbol: Name: ID: |
SST somatostatin GFS:1218 |
Gene name: | SST |
Chromosome: | 3q28 |
Previous Symbols: | |
Previous Names: | |
Aliases: | SMST |
Name Aliases: | somatostatin-14, |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:98326 | Rat Genome Database ID: | RGD:3761 |
HGNC ID: | HGNC:11329 | RefSeq IDs: | NM_001048 |
Entrez Gene ID: | 6750 | Ensembl Gene ID: | ENSG00000157005 |
VEGA IDs: | OTTHUMG00000156462 | UniProt ID: | P61278 |
UCSC ID: | uc003frn.2 | OMIM ID: | 182450 |
Pubmed: | PMID6126875 PMID 6142531 | ||
CCDS IDs: | CCDSCCDS3288.1 |
Somatostatin (also known as growth hormone-inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF)) is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G-protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Somatostatin inhibits the release of somatotropin.
Products for SST gene
Catalog | Product Name | Application | Company |
GFS:E01218 | somatostatin; ELISA kit | ELISA | n/a |
GFS:A01218 | somatostatin; Anti | ANTIBODIES | n/a |
GFS:P01218 | somatostatin; Protien | Protien | n/a |