Symbol: Name: ID: |
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 GFS:782 |
Gene name: | ST3GAL5 |
Chromosome: | 2p11.2 |
Previous Symbols: | SIAT9 |
Previous Names: | sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) |
Aliases: | ST3GalV, SIATGM3S |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1339963 | Rat Genome Database ID: | RGD:620875 |
HGNC ID: | HGNC:10872 | RefSeq IDs: | NM_001042437 |
Entrez Gene ID: | 8869 | Ensembl Gene ID: | ENSG00000115525 |
VEGA IDs: | OTTHUMG00000130171 | UniProt ID: | Q9UNP4 |
UCSC ID: | uc002sqq.1 | OMIM ID: | 604402 |
Pubmed: | PMID9822625 | ||
CCDS IDs: | CCDSCCDS1986.2 CCDS CCDS42705.1 |
Lactosylceramide alpha-2,3-sialyltransferase is an enzyme that in humans is encoded by the ST3GAL5 gene. Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Catalyzes the formation of ganglioside GM3 (alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide).
Products for ST3GAL5 gene
Catalog | Product Name | Application | Company |
GFS:E00782 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5; ELISA kit | ELISA | n/a |
GFS:A00782 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5; Anti | ANTIBODIES | n/a |
GFS:P00782 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5; Protien | Protien | n/a |