Symbol: Name: ID: |
SPO11 SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae) GFS:1142 |
Gene name: | SPO11 |
Chromosome: | 20q13.31 |
Previous Symbols: | |
Previous Names: | SPO11, meiotic protein covalently bound to DSB (S. cerevisiae)-like, "SPO11 meiotic protein covalently bound to DSB-like (S. cerevisiae)" |
Aliases: | CT35 |
Name Aliases: | cancer/testis antigen 35 |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1349669 | Rat Genome Database ID: | RGD:1306454 |
HGNC ID: | HGNC:11250 | RefSeq IDs: | NM_012444 |
Entrez Gene ID: | 23626 | Ensembl Gene ID: | ENSG00000054796 |
VEGA IDs: | OTTHUMG00000032817 | UniProt ID: | Q9Y5K1 |
UCSC ID: | uc002xye.2 | OMIM ID: | 605114 |
Pubmed: | PMID10534401 | ||
CCDS IDs: | CCDSCCDS13456.1 CCDS CCDS13457.1 |
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq].
Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination (By similarity).
Products for SPO11 gene
Catalog | Product Name | Application | Company |
GFS:E01142 | SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae); ELISA kit | ELISA | n/a |
GFS:A01142 | SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae); Anti | ANTIBODIES | n/a |
GFS:P01142 | SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae); Protien | Protien | n/a |