Symbol: Name: ID: |
TSPO translocator protein (18kDa) GFS:1430 |
Gene name: | TSPO |
Chromosome: | 22q13.3 |
Previous Symbols: | BZRP |
Previous Names: | benzodiazapine receptor (peripheral) |
Aliases: | PBR, MBR, PKBS, mDRC, DBI, IBP, pk18 |
Name Aliases: | peripheral-type benzodiazepine receptor/recognition site |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:88222 | Rat Genome Database ID: | RGD:2228 |
HGNC ID: | HGNC:1158 | RefSeq IDs: | NM_000714 |
Entrez Gene ID: | 706 | Ensembl Gene ID: | ENSG00000100300 |
VEGA IDs: | OTTHUMG00000150573 | UniProt ID: | B1AH88 |
UCSC ID: | uc003bdo.2 | OMIM ID: | 109610 |
Pubmed: | PMID1326278 PMID 1847678 PMID 16822554 | ||
CCDS IDs: | CCDSCCDS14046.1 CCDS CCDS33661.1 |
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity).
Products for TSPO gene
Catalog | Product Name | Application | Company |
GFS:E01430 | translocator protein (18kDa); ELISA kit | ELISA | n/a |
GFS:A01430 | translocator protein (18kDa); Anti | ANTIBODIES | n/a |
GFS:P01430 | translocator protein (18kDa); Protien | Protien | n/a |