Symbol: Name: ID: |
RAB25 RAB25, member RAS oncogene family GFS:7110 |
Gene name: | RAB25 |
Chromosome: | 1q22 |
Previous Symbols: | |
Previous Names: | |
Aliases: | CATX-8 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1858203 | Rat Genome Database ID: | RGD:1308447 |
HGNC ID: | HGNC:18238 | RefSeq IDs: | NM_020387 |
Entrez Gene ID: | 57111 | Ensembl Gene ID: | ENSG00000132698 |
VEGA IDs: | OTTHUMG00000017457 | UniProt ID: | P57735 |
UCSC ID: | uc001fnc.2 | OMIM ID: | 612942 |
Pubmed: | PMID11697911 | ||
CCDS IDs: | CCDSCCDS41413.1 |
Ras-related protein Rab-25 is a protein that in humans is encoded by the RAB25 gene.
RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007 [PubMed 17925226]).[supplied by OMIM, Aug 2009]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Increases the rates of ovarian and breast cancers progression and aggressiveness by modulating cellular processes such as proliferation, survival and migration of epithelial tumor cells. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
Products for RAB25 gene
Catalog | Product Name | Application | Company |
GFS:E07110 | RAB25, member RAS oncogene family; ELISA kit | ELISA | n/a |
GFS:A07110 | RAB25, member RAS oncogene family; Anti | ANTIBODIES | n/a |
GFS:P07110 | RAB25, member RAS oncogene family; Protien | Protien | n/a |