Symbol: Name: ID: |
RAB11FIP3 RAB11 family interacting protein 3 (class II) GFS:6310 |
Gene name: | RAB11FIP3 |
Chromosome: | 16p13.3 |
Previous Symbols: | |
Previous Names: | |
Aliases: | KIAA0665, Rab11-FIP3, eferin |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2444431 | Rat Genome Database ID: | RGD:1308952 |
HGNC ID: | HGNC:17224 | RefSeq IDs: | NM_001142272 |
Entrez Gene ID: | 9727 | Ensembl Gene ID: | ENSG00000090565 |
VEGA IDs: | OTTHUMG00000047843 | UniProt ID: | O75154 |
UCSC ID: | uc002chf.2 | OMIM ID: | 608738 |
Pubmed: | PMID9734811 PMID 11481332 | ||
CCDS IDs: | CCDSCCDS32351.1 CCDS CCDS45364.1 |
Rab11 family-interacting protein 3 is a protein that in humans is encoded by the RAB11FIP3 gene.
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008].
Function: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton.
Products for RAB11FIP3 gene
Catalog | Product Name | Application | Company |
GFS:E06310 | RAB11 family interacting protein 3 (class II); ELISA kit | ELISA | n/a |
GFS:A06310 | RAB11 family interacting protein 3 (class II); Anti | ANTIBODIES | n/a |
GFS:P06310 | RAB11 family interacting protein 3 (class II); Protien | Protien | n/a |