Symbol: Name: ID: |
KLF3 Kruppel-like factor 3 (basic) GFS:5622 |
Gene name: | KLF3 |
Chromosome: | 4p16.1-p15.2 |
Previous Symbols: | |
Previous Names: | |
Aliases: | BKLF |
Name Aliases: | basic Kruppel-like factor |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1342773 | Rat Genome Database ID: | RGD:1593290 |
HGNC ID: | HGNC:16516 | RefSeq IDs: | NM_016531 |
Entrez Gene ID: | 51274 | Ensembl Gene ID: | ENSG00000109787 |
VEGA IDs: | OTTHUMG00000097821 | UniProt ID: | P57682 |
UCSC ID: | uc003gth.3 | OMIM ID: | 609392 |
Pubmed: | PMID18391014 | ||
CCDS IDs: | CCDSCCDS3444.1 |
Krueppel-like factor 3 is a protein that in humans is encoded by the KLF3 gene.KLF3 is a member of the Krüppel-like factors family of transcription factors. KLF3 primarily represses transcription through the transcriptional corepressor C-terminal binding protein (CtBP). KLF3's PVDLT (amino acids 61-65) domain, present in its N-terminal variable region, is necessary for its interaction with CtBP. The repression mediated through KLF3 is also partially dependent on the sumoylation of its K10 and K197. Within KLF3's C-terminal, which is highly conserved throughout the KLF family, resides three C2H2 zinc fingers that preferentially bind the site NRG GNG NGR (where R is a purine).
Function: Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis (By similarity)
Products for KLF3 gene
Catalog | Product Name | Application | Company |
GFS:E05622 | Kruppel-like factor 3 (basic); ELISA kit | ELISA | n/a |
GFS:A05622 | Kruppel-like factor 3 (basic); Anti | ANTIBODIES | n/a |
GFS:P05622 | Kruppel-like factor 3 (basic); Protien | Protien | n/a |