Symbol: Name: ID: |
KLF17 Kruppel-like factor 17 GFS:7651 |
Gene name: | KLF17 |
Chromosome: | 1p34.1 |
Previous Symbols: | ZNF393 |
Previous Names: | zinc finger protein 393 |
Aliases: | Zfp393, FLJ40160 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2181068 | Rat Genome Database ID: | RGD:1307711 |
HGNC ID: | HGNC:18830 | RefSeq IDs: | NM_173484 |
Entrez Gene ID: | 128209 | Ensembl Gene ID: | ENSG00000171872 |
VEGA IDs: | OTTHUMG00000009664 | UniProt ID: | Q5JT82 |
UCSC ID: | uc001clp.2 | OMIM ID: | 609602 |
Pubmed: | PMID16460907 | ||
CCDS IDs: | CCDSCCDS508.1 |
Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene.
Function: Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity).
Products for KLF17 gene
Catalog | Product Name | Application | Company |
GFS:E07651 | Kruppel-like factor 17; ELISA kit | ELISA | n/a |
GFS:A07651 | Kruppel-like factor 17; Anti | ANTIBODIES | n/a |
GFS:P07651 | Kruppel-like factor 17; Protien | Protien | n/a |