Symbol: Name: ID: |
KLF13 Kruppel-like factor 13 GFS:3196 |
Gene name: | KLF13 |
Chromosome: | 15 |
Previous Symbols: | |
Previous Names: | |
Aliases: | RFLAT-1, BTEB3, NSLP1, FKLF-2 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1354948 | Rat Genome Database ID: | RGD:1565099 |
HGNC ID: | HGNC:13672 | RefSeq IDs: | NM_015995 |
Entrez Gene ID: | 51621 | Ensembl Gene ID: | ENSG00000169926 |
VEGA IDs: | OTTHUMG00000129269 | UniProt ID: | Q9Y2Y9 |
UCSC ID: | uc001zfo.2 | OMIM ID: | 605328 |
Pubmed: | PMID10415854 PMID 10023774 | ||
CCDS IDs: | CCDSCCDS10025.1 |
Kruppel-like factor 13, also known as KLF13, is a protein that in humans is encoded by the KLF13 gene.
KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).[supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.
Function: Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.
Products for KLF13 gene
Catalog | Product Name | Application | Company |
GFS:E03196 | Kruppel-like factor 13; ELISA kit | ELISA | n/a |
GFS:A03196 | Kruppel-like factor 13; Anti | ANTIBODIES | n/a |
GFS:P03196 | Kruppel-like factor 13; Protien | Protien | n/a |