Symbol: Name: ID: |
FBXW5 F-box and WD repeat domain containing 5 GFS:3157 |
Gene name: | FBXW5 |
Chromosome: | 9q34.3 |
Previous Symbols: | |
Previous Names: | F-box and WD-40 domain protein 5 |
Aliases: | DKFZP434B205, MGC20962, Fbw5 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1354731 | Rat Genome Database ID: | RGD:1305661 |
HGNC ID: | HGNC:13613 | RefSeq IDs: | NM_018998 |
Entrez Gene ID: | 54461 | Ensembl Gene ID: | ENSG00000159069 |
VEGA IDs: | OTTHUMG00000020967 | UniProt ID: | Q969U6 |
UCSC ID: | uc004cjx.2 | OMIM ID: | 609072 |
Pubmed: | |||
CCDS IDs: | CCDSCCDS7014.1 |
F-box/WD repeat-containing protein 5 is a protein that in humans is encoded by the FBXW5 gene.
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008].
Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).
Products for FBXW5 gene
Catalog | Product Name | Application | Company |
GFS:E03157 | F-box and WD repeat domain containing 5; ELISA kit | ELISA | n/a |
GFS:A03157 | F-box and WD repeat domain containing 5; Anti | ANTIBODIES | n/a |
GFS:P03157 | F-box and WD repeat domain containing 5; Protien | Protien | n/a |