Symbol: Name: ID: |
CLEC4A C-type lectin domain family 4, member A GFS:2905 |
Gene name: | CLEC4A |
Chromosome: | 12p13 |
Previous Symbols: | CLECSF6 |
Previous Names: | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 |
Aliases: | DCIR, DDB27 |
Name Aliases: | |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:1349412 | Rat Genome Database ID: | RGD:1359662 |
HGNC ID: | HGNC:13257 | RefSeq IDs: | NM_016184 |
Entrez Gene ID: | 50856 | Ensembl Gene ID: | ENSG00000111729 |
VEGA IDs: | UniProt ID: | Q9UMR7 | |
UCSC ID: | uc001qtz.1 | OMIM ID: | 605306 |
Pubmed: | PMID10438934 | ||
CCDS IDs: | CCDSCCDS8590.1 CCDS CCDS8591.1 CCDS CCDS8592.1 CCDS CCDS41745.1 |
C-type lectin domain family 4 member A is a protein that in humans is encoded by the CLEC4A gene.
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq].
Function: May be involved in regulating immune reactivity. May play a role in modulating dendritic cells (DC) differentiation and/or maturation. May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation.
Products for CLEC4A gene
Catalog | Product Name | Application | Company |
GFS:E02905 | C-type lectin domain family 4, member A; ELISA kit | ELISA | n/a |
GFS:A02905 | C-type lectin domain family 4, member A; Anti | ANTIBODIES | n/a |
GFS:P02905 | C-type lectin domain family 4, member A; Protien | Protien | n/a |