Symbol: Name: ID: |
CLEC10A C-type lectin domain family 10, member A GFS:6002 |
Gene name: | CLEC10A |
Chromosome: | 17p13.2 |
Previous Symbols: | CLECSF13, CLECSF14 |
Previous Names: | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived) |
Aliases: | HML2, HML, CD301 |
Name Aliases: | macrophage lectin 2 (calcium dependent) |
Locus Type: | gene with protein product |
Mouse Genome Database ID: | MGI:2385729 | Rat Genome Database ID: | RGD:621158 |
HGNC ID: | HGNC:16916 | RefSeq IDs: | NM_006344 |
Entrez Gene ID: | 10462 | Ensembl Gene ID: | ENSG00000132514 |
VEGA IDs: | UniProt ID: | Q8IUN9 | |
UCSC ID: | uc002gej.2 | OMIM ID: | 605999 |
Pubmed: | PMID8598452 | ||
CCDS IDs: | CCDSCCDS11087.1 CCDS CCDS45597.1 |
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Function: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Products for CLEC10A gene
Catalog | Product Name | Application | Company |
GFS:E06002 | C-type lectin domain family 10, member A; ELISA kit | ELISA | n/a |
GFS:A06002 | C-type lectin domain family 10, member A; Anti | ANTIBODIES | n/a |
GFS:P06002 | C-type lectin domain family 10, member A; Protien | Protien | n/a |